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l�ll Heberden oration 1979: human aberrations of purine metabolism and their significance for rheumatology Seegmiller JEAnn Rheum Dis 1980[Apr]; 39 (2): 103-17�|Adenosine Deaminase/deficiency[MESH]|Adult[MESH]|Child[MESH]|Female[MESH]|Gout/classification/enzymology[MESH]|Humans[MESH]|Hypoxanthine Phosphoribosyltransferase/deficiency[MESH]|Immunologic Deficiency Syndromes/enzymology[MESH]|Lesch-Nyhan Syndrome/diagnosis/etiology[MESH]|Male[MESH]|Pregnancy[MESH]|Purine-Nucleoside Phosphorylase/deficiency[MESH]|Purine-Pyrimidine Metabolism, Inborn Errors/*enzymology[MESH]|Purines/metabolism[MESH]|Rheumatic Diseases/*enzymology/genetics[MESH]|Ribose-Phosphate Pyrophosphokinase/metabolism[MESH]|T-Lymphocytes/enzymology[MESH]|Uric Acid/urine[MESH] |