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lüll Chemical structure and biological activity of the diazepines Danneberg P; Weber KHBr J Clin Pharmacol 1983[]; 16 Suppl 2 (Suppl 2): 231S-244SSince the introduction of chlordiazepoxide and diazepam many diazepines have been developed. Use of these drugs is increasing and considerable knowledge has accumulated about their mechanisms of action. The structural and pharmacological properties of these drugs are surveyed briefly.|*Anti-Anxiety Agents/pharmacology[MESH]|Acetylcholine/physiology[MESH]|Aggression/drug effects[MESH]|Animals[MESH]|Anxiety[MESH]|Autonomic Nervous System/drug effects[MESH]|Behavior, Animal/drug effects[MESH]|Behavior/drug effects[MESH]|Benzodiazepines[MESH]|Chemical Phenomena[MESH]|Chemistry[MESH]|Dopamine/physiology[MESH]|Drug Interactions[MESH]|Drug Tolerance[MESH]|Glycine/physiology[MESH]|Humans[MESH]|Motor Neurons/drug effects[MESH]|Muscle Tonus/drug effects[MESH]|Norepinephrine/physiology[MESH]|Receptors, Cell Surface/isolation & purification[MESH]|Receptors, GABA-A[MESH]|Receptors, Neurotransmitter/drug effects[MESH]|Serotonin/physiology[MESH]|Sleep/drug effects[MESH]|Structure-Activity Relationship[MESH]|Substance-Related Disorders[MESH]|gamma-Aminobutyric Acid/physiology[MESH] |