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A review of the Zollinger-Ellison syndrome--with particular reference to a patient treated with cimetidine Wyke RJ; Hill GL; Axon ATPostgrad Med J 1979[Oct]; 55 (648): 716-20A case of the Zollinger-Ellison syndrome, presented with watery diarrhoea, malabsorption and multiple duodenal ulcers. Resection of a gastrinoma from the head of the pancreas was ineffective. Cimetidine, administered for more than 30 months produced an immediate and sustained relief of symptoms with a gain in weight of 19 kg and improvement of the biochemical features of malabsorption. Gastric acid secretion has been markedly inhibited and duodenal ulceration healed.|Aged[MESH]|Cimetidine/*therapeutic use[MESH]|Guanidines/*therapeutic use[MESH]|Humans[MESH]|Male[MESH]|Pancreatic Ducts/diagnostic imaging[MESH]|Radiography[MESH]|Zollinger-Ellison Syndrome/diagnostic imaging/*drug therapy/surgery[MESH] |
