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New concepts of digitalis Wycoff CCCalif Med 1969[Dec]; 111 (6): 423-32The data presented in this review have substantiated the following ideas:* There is a direct relationship between digitalis dosage and myocardial contractile force. A small dose of digitalis produces a small increase of the contractile force of the heart and a large dose increases the force of the heart's contraction by a much greater amount, whether the heart is normal, has a poor reserve, or is in frank failure.* Digitalis is of benefit to the patient with cardiovascular disease whether his heart is in failure or not.|*Digitalis Glycosides/administration & dosage/adverse effects/pharmacology[MESH]|Animals[MESH]|Cardiomyopathies/drug therapy[MESH]|Coronary Disease/drug therapy[MESH]|Dogs[MESH]|Heart/drug effects[MESH]|Hemodynamics/drug effects[MESH]|Humans[MESH]|Postoperative Complications/drug therapy[MESH]|Preoperative Care[MESH]|Rabbits[MESH]|Shock/drug therapy[MESH]|Surgical Procedures, Operative[MESH]|Thoracoscopy[MESH] |
