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  lüll Childhood autism  A review of the clinical and experimental literature Ornitz EMCalif Med  1973[Apr]; 118 (4): 21-47This review of the literature on childhood autism discusses the clinical  characteristics, differential diagnosis, prognosis and treatment of the autistic  behavioral syndrome from a developmental perspective. It includes a discussion of  the influence of prenatal and perinatal antecedents, genetic and socio-familial  factors, and epidemiologic considerations. Neurologic, electro-encephalographic  and experimental neurophysiologic, metabolic, biochemical and hematologic  investigations are reviewed. Special emphasis has been given to the changing  clinical manifestations which accompany maturation and to the problems of  recognition of childhood autism in the very young child.|*Autistic Disorder/complications/diagnosis/epidemiology/genetics/therapy[MESH]|Aphasia/complications[MESH]|Child Behavior Disorders/complications[MESH]|Child, Preschool[MESH]|Developmental Disabilities[MESH]|Diagnosis, Differential[MESH]|Electroencephalography[MESH]|Family Characteristics[MESH]|Hematologic Diseases/complications[MESH]|Humans[MESH]|Infant[MESH]|Maternal Deprivation[MESH]|Parent-Child Relations[MESH]|Prognosis[MESH]|Psychotherapy[MESH]|Socioeconomic Factors[MESH]|Speech Therapy[MESH] |