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lüll The pathophysiology and clinical aspects of hypercalcemic disorders Lee DB; Zawada ET; Kleeman CRWest J Med 1978[Oct]; 129 (4): 278-320FOR THE PURPOSES OF THIS REVIEW, THE VAST AND INCREASINGLY COMPLEX SUBJECT OF HYPERCALCEMIC DISORDERS CAN BE BROKEN DOWN INTO THE FOLLOWING CATEGORIES: (1) Physiochemical state of calcium in circulation. (2) Pathophysiological basis of hypercalcemia. (3) Causes of hypercalcemia encountered in clinical practice: causes indicated by experience at the University of California, Los Angeles; neoplasia; hyperparathyroidism; nonparathyroid endocrinopathies; pharmacological agents; possible increased sensitivity to vitamin D; miscellaneous causes. (4) Clinical manifestations and diagnostic considerations of hypercalcemic disorders. (5) The management of hypercalcemic disorders: general measures; measures for lowering serum calcium concentration; measures for correcting primary causes-the management of asymptomatic hyperparathyroidism.|*Hypercalcemia/chemically induced/etiology/genetics/physiopathology/therapy[MESH]|Adolescent[MESH]|Adult[MESH]|Aged[MESH]|Calcium/blood[MESH]|Child[MESH]|Child, Preschool[MESH]|Drug-Related Side Effects and Adverse Reactions[MESH]|Female[MESH]|Granulomatous Disease, Chronic/complications[MESH]|Humans[MESH]|Hyperparathyroidism, Secondary/complications[MESH]|Hyperparathyroidism/complications[MESH]|Hypothyroidism/complications[MESH]|Infant[MESH]|Infant, Newborn[MESH]|Male[MESH]|Middle Aged[MESH]|Neoplasms/complications[MESH]|Sarcoidosis/complications[MESH] |