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lüll The first characterized carbapenem-resistant Bacteroides fragilis strain from Croatia and the case study for it Bogdan M; Peric L; Ordog K; Vukovic D; Urban E; Soki JActa Microbiol Immunol Hung 2018[Aug]; 65 (3): 317-323An imipenem-resistant Bacteroides fragilis strain was isolated from the blood of a 72-year-old male patient with a urinary bladder tumor in Osijek, Croatia. This strain was also resistant to ampicillin, piperacillin/tazobactam, cefoxitin, clindamycin, tetracycline, and harbored cfiA, ermF, and tetQ genes where the high-level expression of the cfiA carbapenem-resistant gene was driven by an IS1187 element. Interestingly, despite the carbapenem-resistant feature of the B. fragilis from blood, the patient relatively easily recovered from the bacteremia. It was the first characterized imipenem-resistant B. fragilis isolate with its case report from Croatia, which confirmed the appearance of carbapenem-resistant B. fragilis strains, that continues worldwide with low incidence and the molecular characteristics vary temporally and geographically.|Aged[MESH]|Anti-Bacterial Agents/*pharmacology[MESH]|Bacterial Infections/*microbiology[MESH]|Bacterial Proteins/genetics/metabolism[MESH]|Bacteroides fragilis/*drug effects/genetics/*isolation & purification[MESH]|Carbapenems/*pharmacology[MESH]|Croatia[MESH]|Drug Resistance, Bacterial[MESH]|Humans[MESH]|Male[MESH]|Microbial Sensitivity Tests[MESH] |