suck pdf from google scholar
unlimited free pdf from europmc29396300    free
PDF from PMC    free
html from PMC    free
PDF vom PMID29396300 :   free
suck pdf from library genesis
English Wikipedia

Nephropedia Template TP (

Twit Text


  • DeepDyve
  • Pubget Overpricing


  • lll
  • Traumatic Brain Injury and Alzheimer s Disease: The Cerebrovascular Link
  • Ramos-Cejudo J; Wisniewski T; Marmar C; Zetterberg H; Blennow K; de Leon MJ; Fossati S
  • EBioMedicine 2018[Feb]; 28 (): 21-30
  • Traumatic brain injury (TBI) and Alzheimer's disease (AD) are devastating neurological disorders, whose complex relationship is not completely understood. Cerebrovascular pathology, a key element in both conditions, could represent a mechanistic link between Abeta/tau deposition after TBI and the development of post concussive syndrome, dementia and chronic traumatic encephalopathy (CTE). In addition to debilitating acute effects, TBI-induced neurovascular injuries accelerate amyloid beta (Abeta) production and perivascular accumulation, arterial stiffness, tau hyperphosphorylation and tau/Abeta-induced blood brain barrier damage, giving rise to a deleterious feed-forward loop. We postulate that TBI can initiate cerebrovascular pathology, which is causally involved in the development of multiple forms of neurodegeneration including AD-like dementias. In this review, we will explore how novel biomarkers, animal and human studies with a focus on cerebrovascular dysfunction are contributing to the understanding of the consequences of TBI on the development of AD-like pathology.
  • |*Cerebrovascular Circulation[MESH]
  • |Alzheimer Disease/*complications/pathology/*physiopathology[MESH]
  • |Animals[MESH]
  • |Blood-Brain Barrier/pathology[MESH]
  • |Brain Injuries, Traumatic/*complications/pathology/*physiopathology[MESH]
  • |Endothelial Cells/pathology[MESH]
  • |Humans[MESH]
  • |Mitochondria/metabolism[MESH]





  • *{{pmid29396300}}
    *<b>[http://www.kidney.de/mlpefetch.php?search=29396300 Traumatic Brain Injury and Alzheimer s Disease: The Cerebrovascular Link ]</b> EBioMedicine 2018; 28() ; 21-30 Ramos-Cejudo J; Wisniewski T; Marmar C; Zetterberg H; Blennow K; de Leon MJ; Fossati S

        *29396300*

    Nephropedia PMID record

    Deutsche Wikipedia - im Artikel

    Hier den unten stehenden Textblock hineinkopieren

    EBioMedicine

    21 .28 2018