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lüll Determination and identification of antibiotic-resistant oral streptococci isolated from active dental infections in adults Loyola-Rodriguez JP; Ponce-Diaz ME; Loyola-Leyva A; Garcia-Cortes JO; Medina-Solis CE; Contreras-Ramire AA; Serena-Gomez EActa Odontol Scand 2018[May]; 76 (4): 229-235OBJECTIVE: To determine and identify antibiotic-resistant bacteria (ARB) of oral streptococci from active dental infections in adults and its association with age and gender. MATERIAL AND METHODS: This cross-sectional study included 59 subjects from 18 to 62 years old. Ninety-eighth samples obtained from the subjects were cultivated in agar plates containing antibiotics amoxicillin/clavulanic acid (A-CA), clindamycin, and moxifloxacin (concentrations of 16, 32 or 64 microg/ml). PCR assay was performed to identify bacterial species. RESULTS: The bacterial species that showed more antibiotic-resistance (AR) was S. mutans (45.9%), followed by S. gordonii (21.6%), S. oralis (17.6%), S. sanguinis (9.5%), S. salivarius (5.4%) and S. sobrinus (0%). Moreover, clindamycin (59.4%) showed the highest frequency of AR. Moxifloxacin and A-CA showed an susceptibility >99.1%, while clindamycin showed the lowest efficacy (93.3%); there was a significant statistically difference (p < .01). The age group between 26 and 50 years old (32.2%) and females (28.8%) showed more multiresistance. Clindamycin showed a statistical difference (p < .05) when comparing groups by gender. CONCLUSIONS: Clindamycin was the antibiotic with the highest frequency of ARB and lower bactericidal effect. Moxifloxacin and A-CA showed the highest efficacy and the lowest ARB frequency. Streptococcus mutans was the bacterial specie that showed an increased frequency of AR.|*Drug Resistance, Multiple, Bacterial[MESH]|Adult[MESH]|Anti-Bacterial Agents/*administration & dosage[MESH]|Clindamycin/administration & dosage[MESH]|Cross-Sectional Studies[MESH]|Dental Plaque/microbiology[MESH]|Female[MESH]|Fluoroquinolones/administration & dosage[MESH]|Humans[MESH]|Male[MESH]|Middle Aged[MESH]|Moxifloxacin[MESH]|Streptococcus mutans/isolation & purification[MESH]|Streptococcus/isolation & purification[MESH]|Tooth Diseases/*drug therapy/*microbiology[MESH] |