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lüll Effect of intra-abdominal pressure on respiratory function in patients undergoing ventral hernia repair Gaidukov KM; Raibuzhis EN; Hussain A; Teterin AY; Smetkin AA; Kuzkov VV; Malbrain ML; Kirov MYWorld J Crit Care Med 2013[May]; 2 (2): 9-16AIM: To determine the influence of intra-abdominal pressure (IAP) on respiratory function after surgical repair of ventral hernia and to compare two different methods of IAP measurement during the perioperative period. METHODS: Thirty adult patients after elective repair of ventral hernia were enrolled into this prospective study. IAP monitoring was performed via both a balloon-tipped nasogastric probe [intragastric pressure (IGP), CiMON, Pulsion Medical Systems, Munich, Germany] and a urinary catheter [intrabladder pressure (IBP), UnoMeterAbdo-Pressure Kit, UnoMedical, Denmark] on five consecutive stages: (1) after tracheal intubation (AI); (2) after ventral hernia repair; (3) at the end of surgery; (4) during spontaneous breathing trial through the endotracheal tube; and (5) at 1 h after tracheal extubation. The patients were in the complete supine position during all study stages. RESULTS: The IAP (measured via both techniques) increased on average by 12% during surgery compared to AI (P < 0.02) and by 43% during spontaneous breathing through the endotracheal tube (P < 0.01). In parallel, the gradient between capital ER, Cyrillicsmall a, Cyrilliccapital ES, Cyrilliccapital O, Cyrillic2 and EtCO2 [capital ER, Cyrillic(small a, Cyrillic-et)CO2] rose significantly, reaching a maximum during the spontaneous breathing trial. The Psmall a, CyrillicO2/FiO2 decreased by 30% one hour after tracheal extubation (P = 0.02). The dynamic compliance of respiratory system reduced intraoperatively by 15%-20% (P < 0.025). At all stages, we observed a significant correlation between IGP and IBP (r = 0.65-0.81, P < 0.01) with a mean bias varying from -0.19 mmHg (2SD 7.25 mmHg) to -1.06 mm Hg (2SD 8.04 mmHg) depending on the study stage. Taking all paired measurements together (n = 133), the median IGP was 8.0 (5.5-11.0) mmHg and the median IBP was 8.8 (5.8-13.1) mmHg. The overall r (2) value (n = 30) was 0.76 (P < 0.0001). Bland and Altman analysis showed an overall bias for the mean values per patient of 0.6 mmHg (2SD 4.2 mmHg) with percentage error of 45.6%. Looking at changes in IAP between the different study stages, we found an excellent concordance coefficient of 94.9% comparing DeltaIBP and DeltaIGP (n = 117). CONCLUSION: During ventral hernia repair, the IAP rise is accompanied by changes in capital ER, Cyrillic(small a, Cyrillic-et)CO2 and Psmall a, CyrillicO2/FiO2-ratio. Estimation of IAP via IGP or IBP demonstrated excellent concordance.ä |