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Feasibility of low-dose contrast medium high pitch CT angiography for the combined evaluation of coronary, head and neck arteries Wang Z; Chen Y; Wang Y; Xue H; Jin Z; Kong L; Cao J; Li SPLoS One 2014[]; 9 (3): e90268PURPOSE: To evaluate the image quality and radiation dose of combined heart, head, and neck CT angiography (CTA) using prospectively electrocardiography (ECG)-triggered high-pitch spiral scan protocol, compared with single coronary CTA. MATERIALS AND METHODS: 151 consecutive patients were prospectively included and randomly divided into three groups. Group 1 (n = 47) underwent combined heart, neck, and head CTA using prospectively ECG-triggered high-pitch spiral (Flash) scan protocol with a single-phase intravenous injection of iodinated contrast and saline flush; Group 2 (n = 51) underwent single coronary CTA with Flash scan protocol; and Group 3 (n = 53) underwent single coronary CTA with prospective sequence scan protocol. All patients were examined on a dual source CT (Definition FLASH). The image quality was determined for each CT study. RESULTS: Patients of scanning protocol Group 1, 2, and 3 showed no significant differences in age, sex, heart rates, and BMI. Evaluation of coronary artery image quality showed comparable results in the three scanning protocol groups on a per patient-based analysis. In group 1, image quality was found to be sufficient to be diagnostic in all arterial segments of carotid arteries. The mean dose-length product (DLP) for group 1 was 256.3+/-24.5 mGyxcm and was significantly higher in comparison with group 2 (93.4+/-19.9 mGyxcm; p < 0.001). However, there was no significant difference of DLP between group 1 and group 3 (254.1+/-69.9 mGyxcm). CONCLUSIONS: The combined heart, neck, and head arteries scan using prospectively electrocardiography (ECG)-triggered high-pitch spiral scan protocol in 1 single examination resulted in an excellent opacification of the aorta, the carotid arteries, and the coronary arteries and provided a good image quality with low radiation dose.|Angiography/*methods[MESH]|Contrast Media/*administration & dosage[MESH]|Coronary Vessels/*diagnostic imaging[MESH]|Dose-Response Relationship, Drug[MESH]|Feasibility Studies[MESH]|Head/*blood supply[MESH]|Humans[MESH]|Neck/*blood supply[MESH]|Tomography, X-Ray Computed[MESH] |
