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Refractory atrial fibrillation effectively treated with ranolazine Vaishnav A; Vaishnav A; Lokhandwala YIndian Heart J 2014[Jan]; 66 (1): 115-8Atrial fibrillation is the most common sustained cardiac arrhythmia which is often troublesome to manage. Currently, rhythm and rate control medications are the mainstays of therapy. In 2 amiodarone-refractory highly symptomatic patients, an innovative approach using ranolazine, which selectively acts on Na+ channels and delays atrial depolarization, was tried successfully.|Acetanilides/*administration & dosage[MESH]|Atrial Fibrillation/diagnosis/*drug therapy/*etiology[MESH]|Cardiomyopathy, Hypertrophic/*complications/diagnosis[MESH]|Dose-Response Relationship, Drug[MESH]|Drug Administration Schedule[MESH]|Electrocardiography/methods[MESH]|Female[MESH]|Follow-Up Studies[MESH]|Humans[MESH]|Male[MESH]|Middle Aged[MESH]|Piperazines/*administration & dosage[MESH]|Ranolazine[MESH]|Recurrence[MESH]|Severity of Illness Index[MESH]|Treatment Outcome[MESH] |
