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lüll Evaluation of video-assisted thoracoscopic surgery for pulmonary metastases: a meta-analysis Dong S; Zhang L; Li W; Du J; Liu X; Chen XPLoS One 2014[]; 9 (1): e85329BACKGROUND: To evaluate the evidence comparing video-assisted thoracic surgery (VATS) and open thoracotomy in the treatment of metastatic lung cancer using meta-analytical techniques. METHODS: A literature search was undertaken until July 2013 to identify the comparative studies evaluating disease-free survival rates and survival rates. The pooled odds ratios (OR) and the 95% confidence intervals (95% CI) were calculated with the fixed or random effect models. RESULTS: Six retrospective studies were included in our meta-analysis. These studies included a total of 546 patients: 235 patients were treated with VATS, and 311 patients were treated with open thoracotomy. The VATS and the thoracotomy did not demonstrate a significant difference in the 1-,3-,5-year survival rates and the 1-year disease-free survival rate. There were significant statistical differences between the 3-year disease free survival rate (p = 0.04), which favored open thoracotomy. CONCLUSIONS: The VATS approach is a safe and feasible treatment in terms of the survival rate for metastatic lung cancer compared with the thoracotomy. The 3-year disease-free survival rate in the VATS group is inferior to that of open thoracotomy. The VATS approach could not completely replace open thoracotomy.|*Thoracic Surgery, Video-Assisted[MESH]|Carcinoma, Non-Small-Cell Lung/mortality/pathology/*surgery[MESH]|Humans[MESH]|Lung Neoplasms/mortality/pathology/*surgery[MESH]|Odds Ratio[MESH]|Pneumonectomy[MESH]|Retrospective Studies[MESH]|Survival Analysis[MESH]|Thoracotomy[MESH]|Treatment Outcome[MESH] |