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lüll Isolated cardiac involvement in primary amyloidosis: presenting as sick sinus syndrome and heart failure Pattanshetty DJ; Bhat PK; Chamberlain WA; Lyons MRTex Heart Inst J 2013[]; 40 (5): 615-8Cardiac amyloidosis is an infiltrative cardiomyopathy with a grave prognosis. Its clinical manifestations include restrictive cardiomyopathy, diastolic heart failure, conduction defects, and arrhythmias. Isolated cardiac involvement and significant conduction disturbances are reported very infrequently. We report a rare case of isolated cardiac involvement in primary amyloidosis, in a 76-year-old man who initially presented with sick sinus syndrome that necessitated permanent pacemaker insertion. Subsequent symptoms of heart failure led to additional evaluation, including an endomyocardial biopsy that revealed primary cardiac amyloidosis. Medical therapy improved the patient's symptoms, and he was discharged from the hospital in stable condition. In addition to discussing the patient's case, we review the relevant medical literature.|Aged[MESH]|Amyloidosis/*complications/diagnosis[MESH]|Biopsy[MESH]|Cardiac Pacing, Artificial[MESH]|Cardiomyopathies/*complications/diagnosis[MESH]|Diagnosis, Differential[MESH]|Echocardiography[MESH]|Electrocardiography[MESH]|Follow-Up Studies[MESH]|Heart Failure, Diastolic/diagnosis/*etiology/therapy[MESH]|Humans[MESH]|Male[MESH]|Myocardium/pathology[MESH]|Sick Sinus Syndrome/diagnosis/*etiology/therapy[MESH] |