Warning: Undefined variable $zfal in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 525
Deprecated: str_replace(): Passing null to parameter #3 ($subject) of type array|string is deprecated in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 525
Warning: Undefined variable $sterm in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 530
 free
Warning: Undefined variable $sterm in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 531
 free
 free
 
English Wikipedia
Nephropedia Template TP (
Twit Text
DeepDyve
Pubget Overpricing |  
lüll
One-year clinical outcomes of BioMatrix-Biolimus A9 eluting stent: the e-BioMatrix multicenter post marketing surveillance registry in India Mehta AB; Chandra P; Dalal J; Shetty P; Desai D; Chocklingam K; Prajapati J; Kumar P; Magarkar V; Vasawada A; Goyal BK; Kumar V; Rao VS; Babu R; Parikh P; Kaul U; Patil A; Mhetre T; Rangnekar HIndian Heart J 2013[Sep]; 65 (5): 593-9OBJECTIVE: The e-BioMatrix is a post marketing multicenter registry with an objective to evaluate the 2 year clinical safety and efficacy outcomes in patients treated with BioMatrix - Biolimus A9 (BA9) drug eluting stents (DES). BACKGROUND: Drug-eluting stents still have late-stage disadvantages that might be attributable to the permanent polymer. BioMatrix a new generation DES containing anti-proliferative drug Biolimus A9 incorporating a biodegradable abluminal coating that leaves a polymer-free stent after drug release enhancing strut coverage while preventing neointimal hyperplasia. METHODS: This interim analysis consists of a total of 1189 patients with 1418 lesions treated with BioMatrix stent who entered this multicenter registry in India. We analyzed the incidence of major adverse cardiac events (MACE) and stent thrombosis (ST) at 1, 6, and 12 months with an extended follow-up of 2 years. Recommended antiplatelet regimen included clopidogrel and aspirin for 12 months. RESULTS: The mean age was 57.6 +/- 10.9 years, 81.8% were males, comorbidity index was 1.20 +/- 1.33, 68% presented with acute coronary syndrome, 49% had hypertension and 40.8% had diabetes mellitus. One-year clinical follow-up was completed in 987 patients at the time of interim analysis. The incidence of MACE is 0.45 for 1544 person-year follow-up. There were only 03 cases of ST (01 late ST) reported during this time. CONCLUSION: This registry demonstrates excellent one-year clinical safety and efficacy of BioMatrix stents. The 1-year result shows that BioMatrix stent may be a suitable alternative as compared to contemporary DESs which are currently available in the market for simple as well complex disease.|*Absorbable Implants[MESH]|*Drug-Eluting Stents[MESH]|*Registries[MESH]|Acute Coronary Syndrome/epidemiology[MESH]|Age Factors[MESH]|Aged[MESH]|Angioplasty, Balloon, Coronary/adverse effects/*instrumentation/methods[MESH]|Coronary Stenosis/diagnostic imaging/mortality/*therapy[MESH]|Female[MESH]|Follow-Up Studies[MESH]|Humans[MESH]|India[MESH]|Male[MESH]|Middle Aged[MESH]|Product Surveillance, Postmarketing[MESH]|Prosthesis Failure[MESH]|Radiography[MESH]|Risk Assessment[MESH]|Sex Factors[MESH]|Sirolimus/*analogs & derivatives/pharmacology[MESH]|Survival Rate[MESH]|Time Factors[MESH]|Treatment Outcome[MESH] |
