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The Melody(R) valve and Ensemble(R) delivery system for transcatheter pulmonary valve replacement McElhinney DB; Hennesen JTAnn N Y Acad Sci 2013[Jul]; 1291 (1): 77-85The Melody(R) transcatheter pulmonary valve (TPV) is a percutaneous valve system designed for the treatment of obstruction and/or regurgitation of prosthetic conduits placed between the right ventricle and pulmonary arteries in patients with congenital heart disease. In 2000, Melody TPV became the first transcatheter valve implanted in a human; in 2006 it became the first transcatheter valve commercially available anywhere in the world; and in 2010 it was launched as the first commercially available transcatheter valve in the United States. In this review, we present the clinical background against which the Melody valve was developed and implemented, introduce the rationale for and challenges of transcatheter valve technology for this population, outline the history and technical details of its development and use, and summarize currently available data concerning the performance of the device.|*Heart Valve Prosthesis[MESH]|Animals[MESH]|Cardiac Catheterization/*instrumentation/methods[MESH]|Heart Defects, Congenital/diagnosis/*surgery[MESH]|Heart Valve Prosthesis Implantation/*instrumentation/methods[MESH]|Humans[MESH]|Pulmonary Valve/*abnormalities/*surgery[MESH]|Treatment Outcome[MESH] |
