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Long-term outcomes after single-balloon enteroscopy in patients with obscure gastrointestinal bleeding Kushnir VM; Tang M; Goodwin J; Hollander TG; Hovis CE; Murad FM; Mullady DK; Azar RR; Jonnalagadda SS; Early DS; Edmundowiz SA; Chen CHDig Dis Sci 2013[Sep]; 58 (9): 2572-9BACKGROUND: Limited data exists on the long-term outcomes of patients with obscure gastrointestinal bleeding (OGIB) following single-balloon enteroscopy (SBE). AIM: To examine the long-term outcomes of patients undergoing SBE for OGIB. METHODS: Consecutive patients undergoing SBE for OGIB at a tertiary care center between 2008 and 2010 were retrospectively identified. Clinical data and SBE findings were extracted from the medical record. Recurrence of OGIB during follow-up through 2012 was assessed by a combination of chart review and telephone interviews. RESULTS: One hundred and forty-seven patients were included in the study. The overall diagnostic yield of SBE was 64.6% (95/147 patients). Findings of SBE included vascular lesions (VLs, 53.7%), small bowel neoplasm (2.7%), inflammatory lesions (4.8%), and normal SBE (35.4%). One hundred and ten patients (56.4% female, mean age 70.6+/-11.3 years) were followed for an average 23.9 months after initial SBE. During follow-up, OGIB recurred in 39.5% of patients in whom a source of OGIB was identified on SBE and 55.9% of patients with normal findings on SBE. OGIB recurred in 47.6% of patients in whom small bowel VLs were treated endoscopically. None of the 13 patients in whom a non-VL lesion was identified as the source of bleeding on SBE experienced recurrent bleeding (p=0.019). CONCLUSIONS: SBE is a safe and valuable method for managing patients with OGIB. More than 50% of patients experienced no recurrent bleeding during 2 years of follow-up after SBE. The long-term management of OGIB due to small bowel VLs remains challenging.|Aged[MESH]|Aged, 80 and over[MESH]|Endoscopy, Gastrointestinal/*statistics & numerical data[MESH]|Female[MESH]|Gastrointestinal Hemorrhage/*diagnosis/*therapy[MESH]|Humans[MESH]|Male[MESH]|Middle Aged[MESH]|Recurrence[MESH]|Retrospective Studies[MESH]|Treatment Outcome[MESH] |
