Warning: Undefined variable $zfal in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 525
Deprecated: str_replace(): Passing null to parameter #3 ($subject) of type array|string is deprecated in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 525
Warning: Undefined variable $sterm in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 530
 free
Warning: Undefined variable $sterm in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 531
 free
 free
Warning: file_get_contents(http://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=23403731&cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests
in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 445
 
English Wikipedia
Nephropedia Template TP (
Twit Text
DeepDyve
Pubget Overpricing |  
lüll
Metabolomic changes in gastrointestinal tissues after whole body radiation in a murine model Ghosh SP; Singh R; Chakraborty K; Kulkarni S; Uppal A; Luo Y; Kaur P; Pathak R; Kumar KS; Hauer-Jensen M; Cheema AKMol Biosyst 2013[Apr]; 9 (4): 723-31Exposure to ionizing radiation (IR) elicits a set of complex biological responses involving gene expression and protein turnover that ultimately manifest as dysregulation of metabolic processes representing the cellular phenotype. Although radiation biomarkers have been reported in urine and serum, they are not informative about IR mediated tissue or organ specific injury. In the present study we report IR induced metabolic changes in gastrointestinal (GI) tissue of CD2F1 mice using ultra-performance liquid chromatography (UPLC) coupled with electrospray time-of-flight mass spectrometry. Post-radiation GI injury is a critical determinant of survival after exposure to IR. Our results show a distinct dose and time dependent response to GI tissue injury.|*Metabolome[MESH]|*Metabolomics[MESH]|Animals[MESH]|Biomarkers/metabolism[MESH]|Cluster Analysis[MESH]|Disease Models, Animal[MESH]|Gastrointestinal Tract/*metabolism/*radiation effects[MESH]|Lipid Metabolism/radiation effects[MESH]|Male[MESH]|Metabolic Networks and Pathways[MESH]|Mice[MESH]|Radiation Injuries, Experimental/metabolism[MESH]|Time Factors[MESH]|Whole-Body Irradiation/*adverse effects[MESH] |
