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lüll Autoimmune enteropathy: a review and update of clinical management Gentile NM; Murray JA; Pardi DSCurr Gastroenterol Rep 2012[Oct]; 14 (5): 380-5Autoimmune enteropathy (AIE) is a rare condition characterized by intractable diarrhea, histologic changes on small intestinal biopsy, and failed response to dietary manipulation that also may present with extraintestinal manifestations. In many patients, immunosuppressive therapies are necessary. Although AIE is more common in infants, adult involvement has also been documented. Much of what is known about AIE has been gathered from case reports and small case series; therefore, more research in this evolving field is needed. IPEX (immunodysregulation polyendocrinopathy enteropathy X-linked syndrome) and APECED (autoimmune phenomena, polyendocrinopathy, candidiasis, and ectodermal dystrophy) are systemic forms of AIE.|*Autoimmune Diseases/diagnosis/physiopathology/therapy[MESH]|Adult[MESH]|Humans[MESH]|Immunosuppressive Agents/*therapeutic use[MESH]|Infant[MESH]|Intestinal Diseases/diagnosis/*immunology/therapy[MESH]|Parenteral Nutrition[MESH] |