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  lüll Cranioplasty after decompressive craniectomy: An institutional audit and analysis  of factors related to complications Sobani ZA; Shamim MS; Zafar SN; Qadeer M; Bilal N; Murtaza SG; Enam SA; Bari MESurg Neurol Int  2011[]; 2 (ä): 123BACKGROUND: Although a relatively simple procedure, cranioplasties have been  associated with high complication rates. Keeping this in perspective, we aimed to  determine the factors associated with immediate and long-term complications of  cranioplasties at our institution. METHODS: A retrospective review of patient  records was carried out for patients having undergone reconstructive  cranioplasties at our institution during the last 10 years (2001-2010). All case  notes, records, and investigations were reviewed and the data were recorded in a  predesigned questionnaire. Complications were recorded along with existing  comorbids and measures taken for their prevention and management. Univariate and  multivariate logistic regression analysis was performed to determine possible  predictors of complications. RESULTS: A total of 96 patients with a mean age of  33 + 15 years were included in the study. Of the sample, 76% (n = 73) had no  comorbids. The leading primary pathology was blunt traumatic brain injuries in  46% (n = 44), followed by cerebrovascular incidents in 24% (n = 23), penetrating  traumatic brain injuries in 12% (n = 11), and tumors in 10% (n = 10) of cases,  with 41% (n = 39) of patients requiring multiple craniotomies. In a mean  follow-up of 386 +/- 615 days, complications were noted in 36.5% (n = 35) of the  patients. Twenty six percent of patients (n = 25) had minor complications which  included breakthrough seizures (15.6%, n = 15), subgaleal collections (3.1%, n =  3), and superficial wound infections (3.1%, n = 3), whereas major complications  (10.4% n = 10) included hydrocephalus (3.1%, n = 3), transient neurological  deficits (3.1%, n = 3), and osteomyelitis (2.1%, n = 2). Univariate and  multivariate analysis revealed External Ventricular Drain (EVD) placement and  parietal flaps to be associated with complications. This could be explained by  the fact that the patients requiring EVD usually have relatively severe head  injuries, increasing the possibility of hydrocephalus. CONCLUSION: We have found  a higher risk of complications of cranioplasty in patients who had EVD placement  and removal prior to their constructive surgery. We however did not find any  association between risks of complications in any other studied variable. We also  did not find any association between intraoperative placement of subgaleal drains  and postoperative risk of subgaleal fluid collections. Overall, our results are  comparable with other reported series on cranioplasties.ä |