Warning: Undefined variable $zfal in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 525
Deprecated: str_replace(): Passing null to parameter #3 ($subject) of type array|string is deprecated in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 525
Warning: Undefined variable $sterm in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 530
free
Warning: Undefined variable $sterm in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 531
free free
English Wikipedia
Nephropedia Template TP (
Twit Text
DeepDyve Pubget Overpricing |
lüll Cellular pathophysiology of ischemic acute kidney injury Bonventre JV; Yang LJ Clin Invest 2011[Nov]; 121 (11): 4210-21Ischemic kidney injury often occurs in the context of multiple organ failure and sepsis. Here, we review the major components of this dynamic process, which involves hemodynamic alterations, inflammation, and endothelial and epithelial cell injury, followed by repair that can be adaptive and restore epithelial integrity or maladaptive, leading to chronic kidney disease. Better understanding of the cellular pathophysiological processes underlying kidney injury and repair will hopefully result in the design of more targeted therapies to prevent the injury, hasten repair, and minimize chronic progressive kidney disease.|Acute Kidney Injury/immunology/pathology/*physiopathology/prevention & control[MESH]|Animals[MESH]|Endothelium, Vascular/pathology/physiopathology[MESH]|Humans[MESH]|Inflammation/immunology/pathology/physiopathology[MESH]|Ischemia/pathology/*physiopathology[MESH]|Ischemic Preconditioning[MESH]|Kidney/*blood supply/pathology[MESH]|Mice[MESH]|Multiple Organ Failure/physiopathology[MESH]|Muscle, Smooth, Vascular/pathology/physiopathology[MESH]|Renal Circulation/physiology[MESH]|Sepsis/physiopathology[MESH] |