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How HIV takes advantage of the cytoskeleton in entry and replication Stolp B; Fackler OTViruses 2011[Apr]; 3 (4): 293-311The host cell cytoskeleton plays a key role in the life cycle of viral pathogens whose propagation depends on mandatory intracellular steps. Accordingly, also the human immunodeficiency virus type 1 (HIV-1) has evolved strategies to exploit and modulate in particular the actin cytoskeleton for its purposes. This review will recapitulate recent findings on how HIV-1 hijacks the cytoskeleton to facilitate entry into, transport within and egress from host cells as well as to commandeer communication of infected with uninfected bystander cells.|*Virus Internalization[MESH]|*Virus Replication[MESH]|Animals[MESH]|Cytoskeleton/metabolism/*virology[MESH]|HIV Infections/metabolism/*virology[MESH]|HIV/genetics/*physiology[MESH]|Humans[MESH] |
