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lüll Retinal hemorrhage associated with perinatal distress in newborns Choi YJ; Jung MS; Kim SYKorean J Ophthalmol 2011[Oct]; 25 (5): 311-6PURPOSE: To describe the ophthalmoscopic features and natural history in a case series of eyes that developed intraocular hemorrhages associated with perinatal distress and to evaluate their clinical courses. METHODS: A retrospective chart review of 289 neonates with a medical history of perinatal distress was conducted. Among these 289 patients (578 eyes), 29 eyes of 17 neonates were found to have had retinal hemorrhages or vitreous hemorrhages (VH). A comprehensive chart review, including details of fundoscopic findings and perinatal history, was conducted. RESULTS: Intraocular hemorrhage was present in 5.5% of the patients. Most hemorrhages (82.7%) were intraretinal. In our population, 17% (n = 5) of hemorrhages resolved within two weeks, but 31% (n = 9) did not resolve even after four weeks. Most hemorrhages spontaneously resolved without any specific sequelae; however, one infant's dense unilateral VH persisted up to three months after birth. When the patient was seen again at 3.5 years of age, she had developed axial myopia and severe amblyopia of the involved eye. CONCLUSIONS: In asphyxiated newborns, the possibility of intraocular hemorrhages should be considered. Long-standing, dense hemorrhages obscuring the macula may lead to severe vision deprivation amblyopia. Therefore, ophthalmic examination should be considered in neonates with perinatal distress, and close observation is necessary for hemorrhages that do not resolve in this amblyogenic age group.|Asphyxia Neonatorum/*complications[MESH]|Female[MESH]|Follow-Up Studies[MESH]|Humans[MESH]|Infant, Newborn[MESH]|Male[MESH]|Ophthalmoscopy[MESH]|Retinal Hemorrhage/diagnosis/*etiology[MESH]|Retrospective Studies[MESH]|Time Factors[MESH]|Visual Acuity[MESH]|Vitrectomy[MESH] |