Warning: Undefined variable $zfal in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 525
Deprecated: str_replace(): Passing null to parameter #3 ($subject) of type array|string is deprecated in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 525
Warning: Undefined variable $sterm in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 530
Warning: Undefined variable $sterm in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 531
 
English Wikipedia
Nephropedia Template TP (
Twit Text
DeepDyve
Pubget Overpricing |  
lüll
Involvement of catecholaminergic medullary pathways in cardiovascular responses to acute changes in circulating volume Cravo SL; Lopes OU; Pedrino GRBraz J Med Biol Res 2011[Sep]; 44 (9): 877-82Water deprivation and hypernatremia are major challenges for water and sodium homeostasis. Cellular integrity requires maintenance of water and sodium concentration within narrow limits. This regulation is obtained through engagement of multiple mechanisms and neural pathways that regulate the volume and composition of the extracellular fluid. The purpose of this short review is to summarize the literature on central neural mechanisms underlying cardiovascular, hormonal and autonomic responses to circulating volume changes, and some of the findings obtained in the last 12 years by our laboratory. We review data on neural pathways that start with afferents in the carotid body that project to medullary relays in the nucleus tractus solitarii and caudal ventrolateral medulla, which in turn project to the median preoptic nucleus in the forebrain. We also review data suggesting that noradrenergic A1 cells in the caudal ventrolateral medulla represent an essential link in neural pathways controlling extracellular fluid volume and renal sodium excretion. Finally, recent data from our laboratory suggest that these structures may also be involved in the beneficial effects of intravenous infusion of hypertonic saline on recovery from hemorrhagic shock.|Afferent Pathways/physiology[MESH]|Aorta/innervation[MESH]|Blood Volume/*physiology[MESH]|Cardiovascular Physiological Phenomena[MESH]|Carotid Arteries/innervation[MESH]|Catecholamines/*physiology[MESH]|Extracellular Fluid/*physiology[MESH]|Humans[MESH]|Kidney/metabolism[MESH]|Medulla Oblongata/*physiology[MESH]|Neural Pathways/physiology[MESH]|Neurons/physiology[MESH]|Sodium/metabolism[MESH]|Water-Electrolyte Balance/*physiology[MESH] |
