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Circadian rhythms in urinary functions: possible roles of circadian clocks?Noh JY; Han DH; Yoon JA; Kim MH; Kim SE; Ko IG; Kim KH; Kim CJ; Cho SInt Neurourol J 2011[Jun]; 15 (2): 64-73Circadian clocks are the endogenous oscillators that harmonize a variety of physiological processes within the body. Although many urinary functions exhibit clear daily or circadian variation in diurnal humans and nocturnal rodents, the precise mechanisms of these variations are as yet unclear. In this review, we briefly introduce circadian clocks and their organization in mammals. We then summarize known daily or circadian variations in urinary function. Importantly, recent findings by others as well as results obtained by us suggest an active role of circadian clock genes in various urinary functions. Finally, we discuss possible research avenues for the circadian control of urinary function.ä |
