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Active transport of proteins into the nucleus Wagner P; Kunz J; Koller A; Hall MNFEBS Lett 1990[Nov]; 275 (1-2): 1-5Nuclear proteins are actively and posttranslationally transported across the nuclear envelope. This transport is a highly selective process that can be divided into two steps, receptor-binding followed by translocation through the nuclear envelope. Receptor-binding is mediated by nuclear localization signals that have been identified in many nuclear proteins. Translocation is energy-dependent and occurs through the nuclear pore complex.|Amino Acid Sequence[MESH]|Animals[MESH]|Biological Transport, Active[MESH]|Cell Compartmentation[MESH]|Molecular Sequence Data[MESH]|Nuclear Envelope/*metabolism/ultrastructure[MESH]|Nuclear Proteins/chemistry/*metabolism[MESH]|Receptors, Cell Surface/metabolism[MESH]|Regulatory Sequences, Nucleic Acid[MESH] |
