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lüll How applicable are clinical practice guidelines to elderly patients with comorbidities?Mutasingwa DR; Ge H; Upshur RECan Fam Physician 2011[Jul]; 57 (7): e253-62OBJECTIVE: To examine the applicability of 10 common clinical practice guidelines (CPGs) to elderly patients with multiple comorbidities. DESIGN: Content analysis of published Canadian CPGs for the following chronic diseases: diabetes, dyslipidemia, dementia, congestive heart failure, depression, osteoporosis, hypertension, gastroesophageal reflux disease, chronic obstructive pulmonary disease, and osteoarthritis. MAIN OUTCOME MEASURES: Presence or absence of 4 key indicators of applicability of CPGs to elderly patients with multiple comorbidities. These indicators include any mention of older adults or people with comorbidities, time needed to treat to benefit in the context of life expectancy, and barriers to implementation of the CPG. RESULTS: Out of the 10 CPGs reviewed, 7 mentioned treatment of the elderly, 8 mentioned people with comorbidities, 4 indicated the time needed to treat to benefit in the context of life expectancy, 5 discussed barriers to implementation, and 7 discussed the quality of evidence. CONCLUSION: This study shows that although most CPGs discuss the elderly population, only a handful of them adequately address issues related to elderly patients with comorbidities. In order to make CPGs more patient centred rather than disease driven, guideline developers should include information on elderly patients with comorbidities.|*Guideline Adherence[MESH]|*Practice Guidelines as Topic[MESH]|Aged[MESH]|Chronic Disease/epidemiology/*therapy[MESH]|Comorbidity[MESH]|Geriatrics/*standards[MESH]|Humans[MESH]|Ontario[MESH]|Outcome Assessment, Health Care/*methods[MESH]|United States/epidemiology[MESH] |