Warning: Undefined variable $zfal in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 525
Deprecated: str_replace(): Passing null to parameter #3 ($subject) of type array|string is deprecated in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 525
Warning: Undefined variable $sterm in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 530
Warning: Undefined variable $sterm in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 531
English Wikipedia
Nephropedia Template TP (
Twit Text
DeepDyve Pubget Overpricing |
lüll Cannabis and its derivatives: review of medical use Leung LJ Am Board Fam Med 2011[Jul]; 24 (4): 452-62BACKGROUND: Use of cannabis is often an under-reported activity in our society. Despite legal restriction, cannabis is often used to relieve chronic and neuropathic pain, and it carries psychotropic and physical adverse effects with a propensity for addiction. This article aims to update the current knowledge and evidence of using cannabis and its derivatives with a view to the sociolegal context and perspectives for future research. METHODS: Cannabis use can be traced back to ancient cultures and still continues in our present society despite legal curtailment. The active ingredient, Delta9-tetrahydrocannabinol, accounts for both the physical and psychotropic effects of cannabis. Though clinical trials demonstrate benefits in alleviating chronic and neuropathic pain, there is also significant potential physical and psychotropic side-effects of cannabis. Recent laboratory data highlight synergistic interactions between cannabinoid and opioid receptors, with potential reduction of drug-seeking behavior and opiate sparing effects. Legal rulings also have changed in certain American states, which may lead to wider use of cannabis among eligible persons. CONCLUSIONS: Family physicians need to be cognizant of such changing landscapes with a practical knowledge on the pros and cons of medical marijuana, the legal implications of its use, and possible developments in the future.|*Cannabis/adverse effects[MESH]|*Phytotherapy/adverse effects[MESH]|Analgesics, Non-Narcotic/adverse effects/*therapeutic use[MESH]|Analgesics, Opioid/therapeutic use[MESH]|Cannabinoids/adverse effects/*therapeutic use[MESH]|Drug Synergism[MESH]|Humans[MESH]|Illicit Drugs/*legislation & jurisprudence[MESH]|Marijuana Abuse[MESH]|Marijuana Smoking/legislation & jurisprudence[MESH]|Neuralgia/drug therapy[MESH]|Pain/*drug therapy[MESH]|United States[MESH] |