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lüll Available and emerging treatments for Parkinson s disease: a review Hickey P; Stacy MDrug Des Devel Ther 2011[]; 5 (ä): 241-54Parkinson's disease is a commonly encountered neurodegenerative disorder primarily found in aged populations. A number of medications are available to control symptoms, although these are less effective in advanced disease. Deep brain stimulation provides a practicable alternative at this stage, although a minority of patients meet the strict criteria for surgery. Novel medications that provide enhanced symptomatic control remain in developmental demand. Both gene and cell-based therapies have shown promise in early clinical studies. A major unmet need is a treatment that slows or stops disease progression.|Animals[MESH]|Antiparkinson Agents/administration & dosage/adverse effects/pharmacology/therapeutic use[MESH]|Deep Brain Stimulation/methods[MESH]|Genetic Therapy/methods[MESH]|Humans[MESH]|Parkinson Disease/drug therapy/metabolism/surgery/*therapy[MESH] |