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lüll The effect of chlorhexidine varnish on root caries: a systematic review Slot DE; Vaandrager NC; Van Loveren C; Van Palenstein Helderman WH; Van der Weijden GACaries Res 2011[]; 45 (2): 162-73OBJECTIVE: The aim of this study was to systematically review the present literature on the effect of chlorhexidine varnish (CHX-V) on root caries. MATERIALS AND METHODS: The MEDLINE-PubMed, the Cochrane-CENTRAL and EMBASE databases were searched through December 2010 to identify any appropriate studies. Root caries incidence and root caries activity were selected as outcome variables. RESULTS: An independent screening of the unique titles and abstracts of 24 MEDLINE-PubMed, 14 Cochrane-CENTRAL and 18 EMBASE papers resulted in 6 publications that met the eligibility criteria. Data extraction provided no conclusive evidence that the application of CHX-V is effective in patients when regular professional oral prophylaxis is performed. If effective, the 40% CHX-V was found to provide a benefit over a control or fluoride varnish. CHX-V at lower concentrations (1 and 10%) may provide protection against root caries in high-risk patients (such as geriatric and xerostomia patients) in the absence of regular professional oral prophylaxis. CONCLUSION: Within the limitations of this review, it may be concluded that in the absence of regular professional tooth cleaning and oral hygiene instructions, CHX-V may provide a beneficial effect in patients in need of special care. The strength of this recommendation is graded as 'weak'.|Cariostatic Agents/administration & dosage/*therapeutic use[MESH]|Chlorhexidine/administration & dosage/*therapeutic use[MESH]|Controlled Clinical Trials as Topic[MESH]|Drug Combinations[MESH]|Ethanol/administration & dosage/therapeutic use[MESH]|Gingival Recession/complications[MESH]|Humans[MESH]|Incidence[MESH]|Paint[MESH]|Polyurethanes/administration & dosage/therapeutic use[MESH]|Root Caries/*drug therapy/epidemiology/etiology[MESH]|Thymol/administration & dosage/therapeutic use[MESH] |