Warning: Undefined variable $zfal in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 525
Deprecated: str_replace(): Passing null to parameter #3 ($subject) of type array|string is deprecated in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 525
Warning: Undefined variable $sterm in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 530
free
Warning: Undefined variable $sterm in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 531
free free
English Wikipedia
Nephropedia Template TP (
Twit Text
DeepDyve Pubget Overpricing |
lüll Skeletonized coronary arteries: pathophysiological and clinical aspects of vascular calcification Serrano CV Jr; Oranges M; Brunaldi V; de M Soeiro A; Torres TA; Nicolau JC; Ramires JAVasc Health Risk Manag 2011[]; 7 (ä): 143-51The role of calcification in coronary artery disease is gaining importance, both in research studies and in clinical application. Calcified plaque has long been considered to be the most important atherosclerotic plaque within the arterial tree and frequently presents a challenge for percutaneous intervention. Current investigations have shown that plaque calcification has a dynamic course that is closely related to the magnitude of vascular inflammation. Numerous inflammatory factors synthesized during the early stages of atherosclerosis induce the expression and activation of osteoblast-like cells localized in the arterial wall that produce calcium. There is no doubt that the role of these factors in calcification associated with coronary artery disease could be a crucial strategic point in prevention and treatment. A number of diagnostic imaging methods have been developed in recent years, but their performance needs to be improved. In this context, we undertook an update on coronary calcification, focusing on physiopathology, clinical implications, and imaging techniques.|Animals[MESH]|Calcinosis/diagnosis/metabolism/*physiopathology[MESH]|Coronary Artery Disease/diagnosis/metabolism/*physiopathology[MESH]|Coronary Vessels/metabolism/pathology/*physiopathology[MESH]|Humans[MESH]|Muscle, Smooth, Vascular/physiopathology[MESH]|Osteogenesis[MESH]|Phenotype[MESH]|Prognosis[MESH]|Signal Transduction[MESH] |