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lüll Treatment options for hypertension in high-risk patients Tsai WCVasc Health Risk Manag 2011[]; 7 (ä): 137-41Patients are considered to be at high risk of cardiovascular events if they have diabetes, chronic kidney disease, stroke, established coronary artery disease, or a coronary artery disease equivalent. Blood pressure-lowering therapy has been shown to reduce cardiovascular events in these patients significantly. Identification of high-risk patients by global risk evaluation is recommended for every hypertensive patient. Treatment of hypertension in high-risk patients with an angiotensin-converting enzyme inhibitor or an angiotensin receptor antagonist, with or without addition of a dihydropyridine calcium channel antagonist, is a reasonable approach based on current clinical trials.|Blood Pressure/drug effects[MESH]|Cardiovascular Agents/*therapeutic use[MESH]|Cardiovascular Diseases/etiology/physiopathology/*prevention & control[MESH]|Drug Therapy, Combination[MESH]|Evidence-Based Medicine[MESH]|Humans[MESH]|Hypertension/complications/*drug therapy/physiopathology[MESH]|Patient Selection[MESH]|Risk Assessment[MESH]|Risk Factors[MESH]|Treatment Outcome[MESH] |