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lüll Radiation exposure from imaging tests: is there an increased cancer risk?Nguyen PK; Wu JCExpert Rev Cardiovasc Ther 2011[Feb]; 9 (2): 177-83The increasing exposure to low-dose radiation from diagnostic testing has prompted renewed interest in evaluating its carcinogenic risk, but quantifying health risk from low-dose radiation exposure remains controversial. The current approach is to adopt the linear non-threshold model, which is commonly applied to high-dose exposure, and apply it to assess risk from low-dose exposure. However, existing data are conflicting and limited to epidemiological studies and/or in vitro analyses. In this article, we will discuss the potential cancer risk from low- and high-dose radiation, their effects on DNA repair response pathways, and the best course of action for patients and providers to minimize risk.|Animals[MESH]|DNA Damage/radiation effects[MESH]|DNA Repair/radiation effects[MESH]|Dose-Response Relationship, Radiation[MESH]|Humans[MESH]|Neoplasms/epidemiology/*etiology/prevention & control[MESH]|Radiation, Ionizing[MESH]|Radiography/*adverse effects[MESH]|Radionuclide Imaging/*adverse effects[MESH]|Risk Assessment[MESH]|Risk Factors[MESH] |