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Metastatic eccrine porocarcinoma: report of a case and review of the literature Marone U; Caraco C; Anniciello AM; Di Monta G; Chiofalo MG; Di Cecilia ML; Mozzillo NWorld J Surg Oncol 2011[Mar]; 9 (ä): 32Eccrine porocarcinoma (EPC) is a rare type of skin cancer arising from the intraepidermal portion of eccrine sweat glands or acrosyringium, representing 0.005-0.01% of all cutaneous tumors. About 20% of EPC will recur and about 20% will metastasize to regional lymph nodes. There is a mortality rate of 67% in patients with lymph node metastases. Although rare, the occurrence of distant metastases has been reported.We report a case of patient with EPC of the left arm, with axillary nodal involvement and subsequent local relapse, treated by complete lymph node dissection and electrochemotherapy (ECT).EPC is an unusual tumor to diagnose. Neither chemotherapy nor radiation therapy has been proven to be of clinical benefit in treating metastatic disease. Although in the current case the short follow-up period is a limitation, we consider in the management of EPC a therapeutic approach involving surgery and ECT, because of its aggressive potential for loregional metastatic spread.|Adult[MESH]|Eccrine Porocarcinoma/*pathology/surgery[MESH]|Humans[MESH]|Lymphatic Metastasis[MESH]|Male[MESH]|Neoplasm Recurrence, Local[MESH]|Sweat Gland Neoplasms/*pathology/surgery[MESH] |
