Warning: Undefined variable $zfal in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 525
Deprecated: str_replace(): Passing null to parameter #3 ($subject) of type array|string is deprecated in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 525
Warning: Undefined variable $sterm in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 530
Warning: Undefined variable $sterm in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 531
 
English Wikipedia
Nephropedia Template TP (
Twit Text
DeepDyve
Pubget Overpricing |  
l�ll
Molecular diagnosis of autosomal dominant polycystic kidney disease Torra Balcells R; Ars Criach ENefrologia 2011[]; 31 (1): 35-43Autosomal dominant polycystic kidney disease (ADPKD) is the most common inherited renal disorder. Its estimated prevalence is 1 per 800 individuals. ADPKD patients constitute 8% of the population on dialysis or kidney transplantation. The disease can be diagnosed using radiological or genetic procedures. Direct genetic diagnosis of the disease can now be performed in Spain; however, it is not an easy or cheap test. This is why every case should be considered individually to determine whether genetic testing is appropriate, and to determine which genetic test is most adequate. Genetic testing in ADPKD is of special interest for living donors and neonatal and sporadic cases. Genetic testing offers the chance of performing prenatal or pre-implantation testing of embryos in families with severe cases of the disease. Also, this will enable the disease to be treated, when specific treatment becomes available, in cases that would not be candidates for treatment without genetic confirmation.|*Mutation[MESH]|Age of Onset[MESH]|DNA Mutational Analysis[MESH]|Databases, Genetic[MESH]|Diagnostic Imaging/economics[MESH]|Genetic Counseling[MESH]|Genetic Linkage[MESH]|Humans[MESH]|Molecular Diagnostic Techniques/economics[MESH]|Mosaicism[MESH]|Polycystic Kidney, Autosomal Dominant/*diagnosis/economics/epidemiology/genetics[MESH]|Preimplantation Diagnosis/economics/methods[MESH]|Prenatal Diagnosis/economics/methods[MESH]|RNA, Messenger/genetics[MESH]|Spain[MESH]|TRPP Cation Channels/genetics[MESH] |