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Lithium use and primary hyperparathyroidism Broome JT; Solorzano CCEndocr Pract 2011[Mar]; 17 Suppl 1 (ä): 31-5OBJECTIVE: To review suspected causes of lithium-induced hyperparathyroidism, disease presentation, underlying pathology, and current recommendations and trends in medical and surgical treatment. METHODS: Relevant literature was reviewed. RESULTS: Lithium carbonate therapy has continued to be a mainstay of treatment for bipolar disease and schizoaffective disorder since its introduction into clinical use. Several metabolic consequences are associated with its long-term use, including hypercalcemia and hyperparathyroidism. CONCLUSIONS: Until further data become available, the surgeon should remain vigilant for the presence of pathologically active glands that may manifest their function at different times during the disease course.|Humans[MESH]|Hyperparathyroidism, Primary/*drug therapy/etiology[MESH]|Lithium Carbonate/*therapeutic use[MESH] |
