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lüll Clinical uses of the medicinal leech: a practical review Porshinsky BS; Saha S; Grossman MD; Beery Ii PR; Stawicki SPJ Postgrad Med 2011[Jan]; 57 (1): 65-71The medicinal leech, Hirudo medicinalis, is an excellent example of the use of invertebrates in the treatment of human disease. Utilized for various medical indications since the ancient times, the medicinal leech is currently being used in a narrow range of well-defined and scientifically-grounded clinical applications. Hirudotherapy is most commonly used in the setting of venous congestion associated with soft tissue replantations and free flap-based reconstructive surgery. This is a comprehensive review of current clinical applications of hirudotherapy, featuring a comprehensive search of all major medical search engines (i.e. PubMed, Google Scholar, ScientificCommons) and other cross-referenced sources. The authors focus on indications, contraindications, practical application/handling of the leech, and therapy-related complications.|*Hirudo medicinalis[MESH]|*Leeching[MESH]|Animals[MESH]|Hirudin Therapy[MESH]|Humans[MESH]|Hyperemia/*therapy[MESH]|Replantation[MESH]|Surgical Flaps/blood supply[MESH] |