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An evolutionary view of chromatography data systems used in bioanalysis McDowall RDBioanalysis 2010[Feb]; 2 (2): 157-65This is a personal view of how chromatographic peak measurement and analyte quantification for bioanalysis have evolved from the manual methods of 1970 to the electronic working possible in 2010. In four decades there have been major changes from a simple chart recorder output (that was interpreted and quantified manually) through simple automation of peak measurement, calculation of standard curves and quality control values and instrument control to the networked chromatography data systems of today that are capable of interfacing with Laboratory Information Management Systems and other IT applications. The incorporation of electronic signatures to meet regulatory requirements offers a great opportunity for business improvement and electronic working.|Chromatography/*history/instrumentation/*methods[MESH]|Computer Communication Networks[MESH]|Guideline Adherence[MESH]|History, 20th Century[MESH]|History, 21st Century[MESH]|Microcomputers[MESH]|Paper[MESH]|Social Control, Formal[MESH]|Statistics as Topic/*history/instrumentation/legislation & jurisprudence/*methods[MESH] |
