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  • Profiling of regulatory microRNA transcriptomes in various biological processes: a review
  • Shah AA; Meese E; Blin N
  • J Appl Genet 2010[]; 51 (4): 501-7
  • A class of small, non-coding ribonucleic acids, termed microRNA (miRNA), has recently emerged as a new key player in the cellular control of gene expression. By either blocking translation or inducing target mRNA degradation, miRNA not only participates in regular biological processes within cells and tissues but is also involved in pathological processes. Many human malignancies have been linked to specific miRNA expression patterns, raising hopes for new approaches to therapy. While such human disease-related mechanisms have been widely discussed and frequently reviewed, miRNA's general significance in animals has been less in editorial focus, despite its obvious role in basic physiological processes, e.g. neurosensory maturation, development of fertility, and hibernation. Using selected examples, this review highlights our current knowledge of miRNA's potential and its promise as a new tool for gene regulation.
  • |*Gene Expression Profiling[MESH]
  • |*Gene Expression Regulation[MESH]
  • |Animals[MESH]
  • |Biological Phenomena/*genetics[MESH]
  • |Disease/genetics[MESH]
  • |Humans[MESH]
  • |MicroRNAs/*genetics/metabolism[MESH]
  • |Signal Transduction/genetics[MESH]





  • *{{pmid21063068}}
    *<b>[http://www.kidney.de/mlpefetch.php?search=21063068 Profiling of regulatory microRNA transcriptomes in various biological processes: a review ]</b> J Appl Genet 2010; 51(4) ; 501-7 Shah AA; Meese E; Blin N

        *21063068*

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    J Appl Genet

    501 4.51 2010