Warning: Undefined variable $zfal in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 525
Deprecated: str_replace(): Passing null to parameter #3 ($subject) of type array|string is deprecated in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 525
Warning: Undefined variable $sterm in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 530
free
Warning: Undefined variable $sterm in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 531
free free
English Wikipedia
Nephropedia Template TP (
Twit Text
DeepDyve Pubget Overpricing |
lüll Neuroendocrine responses to hypoglycemia Tesfaye N; Seaquist ERAnn N Y Acad Sci 2010[Nov]; 1212 (ä): 12-28The counterregulatory response to hypoglycemia is a complex and well-coordinated process. As blood glucose concentration declines, peripheral and central glucose sensors relay this information to central integrative centers to coordinate neuroendocrine, autonomic, and behavioral responses and avert the progression of hypoglycemia. Diabetes, both type 1 and type 2, can perturb these counterregulatory responses. Moreover, defective counterregulation in the setting of diabetes can progress to hypoglycemia unawareness. While the mechanisms that underlie the development of hypoglycemia unawareness are not completely known, possible causes include altered sensing of hypoglycemia by the brain and/or impaired coordination of responses to hypoglycemia. Further study is needed to better understand the intricacies of the counterregulatory response and the mechanisms contributing to the development of hypoglycemia unawareness.|Animals[MESH]|Blood Glucose/metabolism[MESH]|Central Nervous System/metabolism/physiopathology[MESH]|Diabetes Mellitus, Type 1/complications/metabolism/physiopathology[MESH]|Diabetes Mellitus, Type 2/complications/metabolism/physiopathology[MESH]|Feedback, Physiological/physiology[MESH]|Humans[MESH]|Hypoglycemia/complications/diagnosis/*physiopathology[MESH]|Models, Biological[MESH]|Neurosecretory Systems/metabolism/*physiopathology[MESH] |