suck pdf from google scholar
unlimited free pdf from europmc21034673    free
PDF from PMC    free
html from PMC    free
PDF vom PMID21034673 :   free
suck pdf from library genesis
English Wikipedia

Nephropedia Template TP (

Twit Text


  • DeepDyve
  • Pubget Overpricing


  • lüll
  • FOXP3 as an X-linked tumor suppressor
  • Wang L; Liu R; Ribick M; Zheng P; Liu Y
  • Discov Med 2010[Oct]; 10 (53): 322-8
  • The FOXP3 gene was initially identified because its mutation caused lethal autoimmune diseases in mice and humans. Mice with heterozygous mutations of FoxP3 (mouse version of the FOXP3 gene) succumb to mammary tumors spontaneously, while those with prostate-specific deletions develop prostate intraepithelial neoplasia. Somatic mutations, deletion, and epigenetic inactivation of FOXP3 are widespread among human breast and prostate cancers. Unlike autosomal tumor suppressor genes that are usually inactivated by mutations in both alleles, X-linked FOXP3 mutations in cancer samples are usually heterozygous, with the wildtype allele selectively inactivated in cancer. This skewed X-inactivation suggests a new approach to reactivation of FOXP3 for cancer therapy.
  • |Animals[MESH]
  • |Breast Neoplasms/genetics/therapy[MESH]
  • |Carcinoma/genetics/therapy[MESH]
  • |Female[MESH]
  • |Forkhead Transcription Factors/genetics/metabolism/*physiology[MESH]
  • |Gene Silencing/physiology[MESH]
  • |Humans[MESH]
  • |Male[MESH]
  • |Mice[MESH]
  • |Models, Biological[MESH]
  • |Prostatic Neoplasms/genetics/therapy[MESH]
  • |Tumor Suppressor Proteins/genetics/metabolism/*physiology[MESH]





  • *{{pmid21034673}}
    *<b>[http://www.kidney.de/mlpefetch.php?search=21034673 FOXP3 as an X-linked tumor suppressor ]</b> Discov Med 2010; 10(53) ; 322-8 Wang L; Liu R; Ribick M; Zheng P; Liu Y

        *21034673*

    Nephropedia PMID record

    Deutsche Wikipedia - im Artikel

    Hier den unten stehenden Textblock hineinkopieren

    Discov Med

    322 53.10 2010