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lüll Gout and its comorbidities Pillinger MH; Goldfarb DS; Keenan RTBull NYU Hosp Jt Dis 2010[]; 68 (3): 199-203Gout is a chronic disease in which excessively high levels of serum urate (hyperuricemia) result in tissue depositions of sodium urate crystals and intermittent inflammatory attacks. Patients who have gout frequently experience a range of comorbidities, which complicates management and affects long-term prognosis. We review some of the more important of these comorbidities and consider the extent to which gout or hyperuricemia may be either a consequence or a cause of these related conditions. In addition, we briefly consider several neurological conditions in which the presence of gout or a high serum urate level may be associated with less disease, rather than more.|Comorbidity[MESH]|Gout Suppressants/therapeutic use[MESH]|Gout/*epidemiology/therapy[MESH]|Humans[MESH]|Hyperuricemia/*epidemiology/therapy[MESH]|Risk Reduction Behavior[MESH]|Treatment Outcome[MESH] |