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lüll Mass spectrometry and renal calculi Penescu M; Purcarea VL; Sisu I; Sisu EJ Med Life 2010[Apr]; 3 (2): 128-36The present review represents a concise and complete survey of the literature covering 2004-2009, concerning the mass spectrometric techniques involved in the structural investigation of renal calculi. After a short presentation of the fundamental mass spectrometric techniques (MALDI-TOF, QTOF, MS-MS) as well as hyphenated methods (GC-MS, LC-MS, CE-MS), an extensive study of the urinary proteome analysis as well as the detection and quantification by mass spectrometry of toxins, drugs and metabolites from renal calculi is presented.|Animals[MESH]|Calcium Oxalate/analysis/urine[MESH]|Chromatography, Liquid/methods[MESH]|Electrophoresis, Capillary/methods[MESH]|Food Contamination/analysis[MESH]|Gas Chromatography-Mass Spectrometry/methods[MESH]|Humans[MESH]|Kidney Calculi/*chemistry/urine[MESH]|Mass Spectrometry/*methods[MESH]|Osteopontin/urine[MESH]|Proteome/analysis[MESH]|Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization/methods[MESH]|Tandem Mass Spectrometry/methods[MESH]|Triazines/toxicity/urine[MESH] |