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Advances in prognostic factors in acute pancreatitis: a mini-review Pavlidis TE; Pavlidis ET; Sakantamis AKHepatobiliary Pancreat Dis Int 2010[Oct]; 9 (5): 482-6BACKGROUND: Early assessment of the severity of acute pancreatitis is essential to the proper management of the disease. It is dependent on the criteria of the Atlanta classification system. DATA SOURCES: PubMed search of recent relevant articles was performed to identify information about the severity and prognosis of acute pancreatitis. RESULTS: The scoring systems included the Ranson's or Glasgow's criteria >/=3, the APACHE II classification system >/=8, and the Balthazar's criteria >/=4 according to the computed tomography enhanced scanning findings. The single factors on admission included age >65 years, obesity, hemoconcentration (>44%), abnormal chest X-ray, creatinine >2 mg/dl, C-reactive protein >150 mg/dl, procalcitonin >1.8 ng/ml, albumin <2.5 mg/dl, calcium <8.5 mg/dl, early hyperglycemia, increased intra-abdominal pressure, macrophage migration inhibitory factor, or a combination of IL-10 >50 pg/ml with calcium <6.6 mg/dl. CONCLUSION: The prediction of the severity of acute pancreatitis is largely based on well defined multiple factor scoring systems as well as several single risk factors.|Acute Disease[MESH]|Humans[MESH]|Pancreatitis/*blood/*diagnosis[MESH]|Prognosis[MESH]|Risk Factors[MESH]|Severity of Illness Index[MESH] |
