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lüll One hundred two patients with pheochromocytoma treated at a single institution since the introduction of laparoscopic adrenalectomy Shen WT; Grogan R; Vriens M; Clark OH; Duh QYArch Surg 2010[Sep]; 145 (9): 893-7HYPOTHESIS: Pheochromocytoma can be safely treated laparoscopically; "subclinical" pheochromocytoma is increasingly common. DESIGN: Retrospective review. SETTING: University hospital. PATIENTS: Patients undergoing adrenalectomy for pheochromocytoma at our institution in 1994 to 2009. INTERVENTIONS: Laparoscopic, hand-assisted, and open adrenalectomy. MAIN OUTCOME MEASURES: Preoperative and postoperative clinical and biochemical data. RESULTS: One hundred two patients (52 women, 50 men) with pheochromocytoma underwent 108 operations. Ninety-seven operations were laparoscopic; 7, open; and 4, converted from laparoscopic to hand assisted or open. Six operations were bilateral; 3 were subtotal cortex-sparing resections. Thirty-four patients (33%) presented with adrenal incidentaloma and minimal symptoms, 28 within the past decade. Ten patients had paragangliomas, 7 of whom underwent laparoscopic resection. The mean (SD) tumor size was 5.3 (2.8) cm. Seven patients had recurrence requiring reoperation; the mean length of time between initial operation and recurrence was 6 years (range, 6 months to 17 years). There were no perioperative deaths. CONCLUSIONS: Laparoscopic adrenalectomy can be safely performed for pheochromocytoma in more than 90% of cases. More than one-third of patients presented with subclinical pheochromocytoma. Patients should be followed up closely because recurrence may develop several years after adrenalectomy.|Adrenal Gland Neoplasms/diagnosis/epidemiology/pathology/*surgery[MESH]|Adrenalectomy/*methods[MESH]|Adult[MESH]|Female[MESH]|Humans[MESH]|Incidental Findings[MESH]|Intra-Aortic Balloon Pumping[MESH]|Laparoscopy[MESH]|Male[MESH]|Middle Aged[MESH]|Neoplasm Recurrence, Local/epidemiology[MESH]|Pheochromocytoma/diagnosis/epidemiology/pathology/*surgery[MESH]|Retrospective Studies[MESH]|Shock, Cardiogenic/epidemiology/therapy[MESH] |