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The iris - a window into the genetics of common and rare eye diseases Morrison PJUlster Med J 2010[Jan]; 79 (1): 3-5Visual examination, without instruments, of the eye allows inspection of the iris, sclera, cornea and, through the iris, some abnormalities of the lens and retina. Several hereditary disorders can easily be recognised by characteristic iris changes. This review discusses changes in the iris, visible lens anomalies, and changes in the cornea surrounding the iris. A genetic diagnosis can help with management of diseases. Some conditions are single gene disorders, some are chromosomal rearrangements, and some are abnormalities of fetal development.|Chromosome Disorders[MESH]|Cornea/*abnormalities/pathology[MESH]|Eye Diseases/diagnosis/genetics/pathology[MESH]|Humans[MESH]|Iris Diseases/*diagnosis/genetics/pathology[MESH]|Iris/*abnormalities/pathology[MESH] |
