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Type I interferon: friend or foe?Trinchieri GJ Exp Med 2010[Sep]; 207 (10): 2053-63Although the role of type I interferon (IFN) in the protection against viral infections has been known and studied for decades, its role in other immunologically relevant scenarios, including bacterial infections, shock, autoimmunity, and cancer, is less well defined and potentially much more complicated.|Animals[MESH]|Autoimmunity/immunology[MESH]|Bacterial Infections/immunology[MESH]|Humans[MESH]|Immunity, Innate[MESH]|Interferon Type I/*immunology[MESH]|Interferon-gamma/immunology[MESH]|Neoplasms/immunology[MESH]|Shock/immunology[MESH]|Signal Transduction/immunology[MESH]|Virus Diseases/immunology[MESH] |
