Warning: Undefined variable $zfal in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 525
Deprecated: str_replace(): Passing null to parameter #3 ($subject) of type array|string is deprecated in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 525
Warning: Undefined variable $sterm in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 530
free
Warning: Undefined variable $sterm in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 531
free free
English Wikipedia
Nephropedia Template TP (
Twit Text
DeepDyve Pubget Overpricing |
lüll Glutamate plasticity in the drunken amygdala: the making of an anxious synapse McCool BA; Christian DT; Diaz MR; Lack AKInt Rev Neurobiol 2010[]; 91 (ä): 205-33Plasticity at glutamatergic synapses is believed to be the cellular correlate of learning and memory. Classic fear conditioning, for example, is dependent upon NMDA-type glutamate receptor activation in the lateral/basolateral amygdala followed by increased synaptic expression of AMPA-type glutamate receptors. This review provides an extensive comparison between the initiation and expression of glutamatergic plasticity during learning/memory and glutamatergic alterations associated with chronic ethanol exposure and withdrawal. The parallels between these neuro-adaptive processes suggest that long-term ethanol exposure might "chemically condition" amygdala-dependent fear/anxiety via the increased function of pre- and post-synaptic glutamate signaling.|*Amygdala/drug effects/pathology/physiopathology[MESH]|Alcoholism/*pathology[MESH]|Animals[MESH]|Ethanol/*pharmacology[MESH]|Glutamic Acid/*metabolism[MESH]|Humans[MESH]|Neuronal Plasticity/*drug effects[MESH]|Receptors, AMPA/metabolism[MESH]|Receptors, N-Methyl-D-Aspartate/metabolism[MESH]|Synapses/*drug effects/physiology[MESH] |