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lüll Taurine and the renal system Chesney RW; Han X; Patters ABJ Biomed Sci 2010[Aug]; 17 Suppl 1 (Suppl 1): S4Taurine participates in a number of different physiologic and biologic processes in the kidney, often reflected by urinary excretion patterns. The kidney is key to aspects of taurine body pool size and homeostasis. This review will examine the renal-taurine interactions relative to ion reabsorption; renal blood flow and renal vascular endothelial function; antioxidant properties, especially in the glomerulus; and the role of taurine in ischemia and reperfusion injury. In addition, taurine plays a role in the renal cell cycle and apoptosis, and functions as an osmolyte during the stress response. The role of the kidney in adaptation to variations in dietary taurine intake and the regulation of taurine body pool size are described. Finally, the protective function of taurine against several kidney diseases is reviewed.|Animals[MESH]|Apoptosis[MESH]|Cell Cycle[MESH]|Humans[MESH]|Ions/metabolism[MESH]|Kidney Diseases/physiopathology[MESH]|Kidney Glomerulus/metabolism[MESH]|Kidney/blood supply/*metabolism[MESH]|Osmolar Concentration[MESH]|Regional Blood Flow[MESH]|Reperfusion Injury/metabolism[MESH]|Taurine/*metabolism[MESH] |