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Spectrum of pulmonary neuroendocrine cell proliferation: diffuse idiopathic pulmonary neuroendocrine cell hyperplasia, tumorlet, and carcinoids Koo CW; Baliff JP; Torigian DA; Litzky LA; Gefter WB; Akers SRAJR Am J Roentgenol 2010[Sep]; 195 (3): 661-8OBJECTIVE: The objectives of this article are to review the radiologic, pathologic, and clinical features of diffuse idiopathic pulmonary neuroendocrine cell hyperplasia, tumorlet, and carcinoids and to discuss the possible role of diffuse idiopathic pulmonary neuroendocrine cell hyperplasia and tumorlet in the development of carcinoids. CONCLUSION: Given the potential significant morbidity of diffuse idiopathic pulmonary neuroendocrine cell hyperplasia and its neoplastic counterparts, it is important to understand and recognize these disease entities. A conceptual continuum of these neuroendocrine entities is suggested.|Carcinoid Tumor/diagnostic imaging/*pathology[MESH]|Cell Proliferation[MESH]|Contrast Media[MESH]|Diagnosis, Differential[MESH]|Humans[MESH]|Lung Neoplasms/diagnostic imaging/*pathology[MESH]|Neuroendocrine Cells/*pathology[MESH]|Neuroendocrine Tumors/diagnostic imaging/*pathology[MESH]|Neurosecretory Systems/pathology[MESH]|Precancerous Conditions/diagnostic imaging/pathology[MESH]|Risk Factors[MESH]|Tomography, X-Ray Computed[MESH] |
